"Visually, Jeff was an intriguing player to watch, because he played guitar - by any conventional standard - all wrong, with it flat across his lap," his publicist Richard Flohil told broadcaster CTV. "But he was a remarkable, a virtuoso player."
The Jeff Healey Band's 1988 Grammy-nominated album See the Light, which included the hit "Angel Eyes", sold more than 1 million copies in the United States.
He played with blues legends BB King and Stevie Ray Vaughn, and recorded with George Harrison, Mark Knopfler and Jimmy Rogers.
His death came a month before the release of his new album, Mess of Blues, which will be his first rock album in eight years.